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Quantum BioPharma’s Secret Weapon: A Dual Engine of Clinical Innovation and Consumer Expansion

Posted by Brittany McNabb at 11:10 AM on Wednesday, April 16th, 2025

From clinical breakthroughs in multiple sclerosis to a fast-growing alcohol detox brand, Quantum BioPharma is bridging biotech innovation with real-world impact.

A Biopharma Platform Tackling Today’s Toughest Health Challenges

Quantum BioPharma Ltd. (NASDAQ: QNTM | CSE: QNTM) is emerging as a dynamic force in the biotechnology sector, developing solutions for two major public health issues: neurodegenerative diseases and alcohol misuse. With a diversified pipeline spanning prescription drugs and over-the-counter consumer products, the company is building an integrated portfolio capable of delivering both near-term commercial gains and long-term medical breakthroughs.

The company’s strategy is uniquely positioned at the intersection of science, innovation, and unmet need — making it one of the few small-cap biotechs advancing both FDA-bound therapeutics and consumer-ready wellness products simultaneously.

Lucid-MS: Targeting the Root Cause of Multiple Sclerosis

At the heart of Quantum’s pharmaceutical program is Lucid-MS, a patented new chemical entity showing early promise in treating multiple sclerosis (MS). Unlike conventional MS drugs that focus on managing inflammation, Lucid-MS addresses the core driver of long-term disability in MS: the breakdown of the myelin sheath — the protective layer around nerve fibers.

Following a successful Phase 1 clinical trial, the drug has been deemed safe and well-tolerated, with therapeutic blood levels observed in healthy participants. Quantum is now preparing to launch a Phase 2 trial in 2026, targeting efficacy in MS patients.

What makes Lucid-MS even more distinctive is Quantum’s collaborative study with Massachusetts General Hospital (MGH), featuring scientists from Harvard Medical School, to validate advanced PET imaging as a way to monitor demyelination in real time. This partnership elevates both the scientific credibility and clinical precision behind Lucid-MS, positioning it as a next-generation therapeutic candidate in a $27 billion global MS treatment market.

unbuzzd™: A Consumer Wellness Product with Scientific Backing

In parallel with its clinical pipeline, Quantum BioPharma is making significant inroads in the consumer wellness market through unbuzzd™, an over-the-counter alcohol detox and recovery beverage developed by its spinout, Celly Nutrition Corp. The product, a fast-acting powder stick formulated by pharmacology experts, is designed to accelerate alcohol metabolism, restore mental clarity, and reduce hangover symptoms.

unbuzzd™ is already making retail waves. Backed by a double-blind, placebo-controlled clinical trial, the beverage demonstrated that it could reduce blood alcohol concentration (BAC) over 40% faster than placebo in many subjects. It’s now available via Amazon and unbuzzd.com, with retail expansion underway in the U.S., Puerto Rico, and the Caribbean through a new distribution agreement with FUSION Distribution Group.

Most recently, unbuzzd™ entered a landmark partnership with AATAC, one of the largest retail networks in the U.S., which connects the product to over 80,000 convenience store locations. This expansion gives unbuzzd™ exposure to leading chains like 7-Eleven, Circle K, Shell, and ampm — significantly scaling its retail footprint.

Multiple Value Streams, One Vision

Quantum BioPharma holds 25.71% ownership in Celly Nutrition and receives up to 7% in royalties from unbuzzd™ sales until a $250M threshold is met — and 3% in perpetuity thereafter. This structure offers upside exposure to the high-growth consumer market while maintaining strategic focus on the pharmaceutical pipeline.

With an improved cash position, enhanced operational efficiency, and momentum across both drug development and consumer wellness fronts, the company is now advancing toward key inflection points on multiple fronts.

A Biotech Story Worth Watching

With a first-in-class MS treatment advancing toward Phase 2 trials, a consumer product already on shelves and gaining market traction, and elite partnerships with global institutions like Harvard and AATAC — Quantum BioPharma stands apart in the small-cap biotech landscape.

It’s not just a company developing drugs. It’s building a platform for impact, backed by scientific validation and commercial momentum.


YOUR NEXT STEPS 

Visit $QNTM HUB On AGORACOM: https://agoracom.com/ir/Quantumbiopharma

Visit $QNTM 5 Minute Research Profile On AGORACOM: https://agoracom.com/ir/Quantumbiopharma/profile

Visit $QNTM Official Verified Discussion Forum On AGORACOM:

https://agoracom.com/ir/Quantumbiopharma/forums/discussion

Watch $QNTM Videos On AGORACOM YouTube Channel:

https://studio.youtube.com/playlist/PLfL457LW0vdK6S1r-_VHqbuWQNDV4fV-D/videos

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Canadian Biotech Quantum BioPharma Nears a Landmark Multiple Sclerosis Breakthrough

Posted by Brittany McNabb at 9:54 AM on Thursday, March 27th, 2025

New Approach Could Redefine How Multiple Sclerosis Is Treated Worldwide

Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) may be on the verge of redefining treatment for multiple sclerosis (MS), a chronic neurological disorder affecting nearly 3 million people worldwide. In a compelling interview on the AGORACOM, Dr. Andrzej Chruscinski, Vice-President of Scientific and Clinical Affairs at Quantum BioPharma, detailed the company’s successful completion of its Phase 1 clinical trial for Lucid-MS, a first-in-class neuroprotective drug targeting demyelination—the core driver of MS progression.

Unlike existing treatments, which primarily focus on managing the immune system and controlling inflammation, Lucid-MS takes aim at protecting and potentially repairing the myelin sheath—the protective layer around nerve cells that degenerates in MS patients. “We’re excited about the potential of Lucid-MS to protect myelin in MS patients as it represents a new direction in the treatment of this disease,” said Quantum BioPharma CEO Zeeshan Saeed.

A Novel Solution to a Persistent Problem

Most MS therapies today only address the inflammatory aspect of the disease, leaving the underlying neurodegeneration largely unaddressed. Lucid-MS changes that narrative.

  • The drug works by preventing the unraveling of the myelin sheath, a process triggered by a chemical modification known as citrullination.

  • Developed over a decade by Dr. Lakshmi Kotra and Dr. Mario Moscarello at the University of Toronto, Lucid-MS targets this key process, aiming to halt disease progression and protect nerve communication.

  • The approach has already shown success in preclinical animal models.

“Think of the myelin sheath like insulation around electrical wiring. When that’s compromised, signals can’t transmit properly,” explained Dr. Chruscinski. “Our drug preserves that insulation, maintaining neural function.”

Phase 1 Trial: Safety Confirmed, Therapeutic Potential Emerges

The recently completed Phase 1 trial focused on evaluating safety and pharmacokinetics in healthy participants. According to Dr. Chruscinski, “Lucid-MS was safe and well-tolerated, with no adverse events. We’re also pleased with the drug levels observed in blood, which we believe are therapeutic.”

This milestone is crucial for advancing to Phase 2, where the company will begin testing Lucid-MS in MS patients to assess efficacy.

What to Expect in Phase 2

The company is actively designing its Phase 2 trial with a projected start in Q1 2026, pending FDA clearance via an Investigational New Drug (IND) application in late 2025.

Key details under consideration:

  • The trial will include roughly 60 MS patients (30 receiving Lucid-MS and 30 on placebo).

  • Outcomes will be measured using MRI scans and clinical assessments to evaluate both biological and functional improvement.

  • While the exact location is yet to be confirmed, Quantum is exploring options to include Canadian sites in recognition of the drug’s Canadian origins.

Support From the Scientific Community

Feedback from global experts at major MS conferences in North America and Europe has been overwhelmingly positive. “The response has been tremendous,” said Dr. Chruscinski. “There’s a real appetite for a drug that targets neurodegeneration, which remains an unmet need in MS.”

This third-party validation underscores the broader scientific and commercial relevance of Quantum BioPharma’s work.

A Human-Centered Mission With Investor Appeal

Dr. Chruscinski also emphasized his personal motivation. “It’s exciting to be part of something that could make a real difference. I was there when the first dose was administered in our Phase 1 trial. That’s a moment I won’t forget.”

While the drug development process remains long and complex, Quantum BioPharma has achieved a significant milestone that positions the company—and Lucid-MS—at the forefront of innovation in MS treatment.

For investors, the opportunity lies in Quantum’s unique approach, successful early data, and a clearly defined path toward a potential market-shifting solution.

Conclusion: A Meaningful Milestone With a Promising Horizon

With a Phase 1 trial successfully completed and a novel therapeutic mechanism unlike anything currently on the market, Quantum BioPharma is emerging as a company to watch in the fight against multiple sclerosis. As it gears up for its Phase 2 trial and FDA engagement, the company stands at a pivotal inflection point—one that could not only deliver long-term value for investors but also reshape the future of MS care.

To hear Dr. Chruscinski explain the science, milestones, and next steps in his own words, watch the full interview here: