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Quantum BioPharma Confronts Extreme Short Pressure Amid Market Imbalances as Borrow Fees Surge Beyond 437%

Posted by Brittany McNabb at 9:55 AM on Friday, June 27th, 2025

Quantum BioPharma (NASDAQ: QNTM / CSE: QNTM) is now facing one of the most severe short pressure environments observed in North American markets this year. The borrow fee on QNTM shares has surged past 437% annually — roughly 1% per trading day — placing it among the highest-cost securities to short across any exchange. These fees signal that brokers are effectively out of lendable inventory and are pricing risk accordingly.

Float Scarcity Driving Volatility Risk

With fewer than 15,000 shares available for borrowing across major prime brokers, QNTM has entered what many refer to as a “locate vacuum.” The company’s public float is approximately 2.6 million shares, making it highly sensitive to buying pressure. In micro-float environments, even small bursts of covering or long-side accumulation can cause rapid price escalation due to a lack of natural sellers and tight liquidity conditions.

Dark Pool Activity Clouds Price Discovery

Adding to concerns is the high proportion of off-exchange short trading. In recent sessions, approximately 59% of QNTM’s daily volume has been routed through dark pools — private trading venues that do not display pre-trade quotes. While such routing is legal, this level of activity can obscure real demand and suppress visible momentum. In an environment where supply is tight and borrow costs are surging, dark pool dominance raises legitimate questions about whether price discovery is functioning as it should.

Echoes of Past Short-Driven Dislocations

The structural setup now surrounding QNTM bears striking similarities to prior market events that resulted in high-profile short squeezes. KaloBios (KBIO) gained over 10,000% in 2015 after its float was effectively locked and borrow availability vanished. GameStop (GME) surged 2,740% in early 2021 under conditions of high borrow fees, float constraints, and elevated short interest. Other comparables include Tilray (TLRY) and KOSS, where borrow fees exceeded 800% during moments of extreme float compression. QNTM’s current borrow rate already exceeds GME’s peak — despite having a much smaller float.

Company Fundamentals Remain Unchanged

While trading volatility has increased, Quantum BioPharma’s operational strategy and clinical programs remain firmly on track. The company recently completed Phase 1 trials for Lucid-MS, a novel treatment designed to repair myelin damage in multiple sclerosis patients. Developed in collaboration with scientists from a Harvard-affiliated teaching hospital, Lucid-MS offers a differentiated approach in a space long dominated by immune suppression therapies. Importantly, the company has made no promotional claims, has not issued new financings, and is not engaged in any stock-related marketing activity.

No Squeeze Assumptions — But Structural Tension Is Clear

A short squeeze is never guaranteed, even with elevated borrow fees and float scarcity. However, the structural tension in QNTM’s trading — characterized by near-zero share availability, high-cost borrow, and dark pool suppression — creates the potential for sudden dislocation if a trigger appears. Any combination of positive news, reduced volume, or insider accumulation could prompt a reflexive covering event in a market ill-equipped to absorb it.

Reaffirming the Need for Market Integrity

Quantum BioPharma has not commented on recent trading behavior but reaffirms its commitment to transparency, scientific advancement, and regulatory compliance. The company supports fair, orderly markets and believes that all participants — including regulators and exchanges — should remain vigilant when structural indicators point to breakdowns in natural price formation. As this situation evolves, investors, analysts, and oversight bodies are encouraged to monitor borrow fees, share availability, and trade routing closely.

Quantum BioPharma’s Secret Weapon: A Dual Engine of Clinical Innovation and Consumer Expansion

Posted by Brittany McNabb at 11:10 AM on Wednesday, April 16th, 2025

From clinical breakthroughs in multiple sclerosis to a fast-growing alcohol detox brand, Quantum BioPharma is bridging biotech innovation with real-world impact.

A Biopharma Platform Tackling Today’s Toughest Health Challenges

Quantum BioPharma Ltd. (NASDAQ: QNTM | CSE: QNTM) is emerging as a dynamic force in the biotechnology sector, developing solutions for two major public health issues: neurodegenerative diseases and alcohol misuse. With a diversified pipeline spanning prescription drugs and over-the-counter consumer products, the company is building an integrated portfolio capable of delivering both near-term commercial gains and long-term medical breakthroughs.

The company’s strategy is uniquely positioned at the intersection of science, innovation, and unmet need — making it one of the few small-cap biotechs advancing both FDA-bound therapeutics and consumer-ready wellness products simultaneously.

Lucid-MS: Targeting the Root Cause of Multiple Sclerosis

At the heart of Quantum’s pharmaceutical program is Lucid-MS, a patented new chemical entity showing early promise in treating multiple sclerosis (MS). Unlike conventional MS drugs that focus on managing inflammation, Lucid-MS addresses the core driver of long-term disability in MS: the breakdown of the myelin sheath — the protective layer around nerve fibers.

Following a successful Phase 1 clinical trial, the drug has been deemed safe and well-tolerated, with therapeutic blood levels observed in healthy participants. Quantum is now preparing to launch a Phase 2 trial in 2026, targeting efficacy in MS patients.

What makes Lucid-MS even more distinctive is Quantum’s collaborative study with Massachusetts General Hospital (MGH), featuring scientists from Harvard Medical School, to validate advanced PET imaging as a way to monitor demyelination in real time. This partnership elevates both the scientific credibility and clinical precision behind Lucid-MS, positioning it as a next-generation therapeutic candidate in a $27 billion global MS treatment market.

unbuzzd™: A Consumer Wellness Product with Scientific Backing

In parallel with its clinical pipeline, Quantum BioPharma is making significant inroads in the consumer wellness market through unbuzzd™, an over-the-counter alcohol detox and recovery beverage developed by its spinout, Celly Nutrition Corp. The product, a fast-acting powder stick formulated by pharmacology experts, is designed to accelerate alcohol metabolism, restore mental clarity, and reduce hangover symptoms.

unbuzzd™ is already making retail waves. Backed by a double-blind, placebo-controlled clinical trial, the beverage demonstrated that it could reduce blood alcohol concentration (BAC) over 40% faster than placebo in many subjects. It’s now available via Amazon and unbuzzd.com, with retail expansion underway in the U.S., Puerto Rico, and the Caribbean through a new distribution agreement with FUSION Distribution Group.

Most recently, unbuzzd™ entered a landmark partnership with AATAC, one of the largest retail networks in the U.S., which connects the product to over 80,000 convenience store locations. This expansion gives unbuzzd™ exposure to leading chains like 7-Eleven, Circle K, Shell, and ampm — significantly scaling its retail footprint.

Multiple Value Streams, One Vision

Quantum BioPharma holds 25.71% ownership in Celly Nutrition and receives up to 7% in royalties from unbuzzd™ sales until a $250M threshold is met — and 3% in perpetuity thereafter. This structure offers upside exposure to the high-growth consumer market while maintaining strategic focus on the pharmaceutical pipeline.

With an improved cash position, enhanced operational efficiency, and momentum across both drug development and consumer wellness fronts, the company is now advancing toward key inflection points on multiple fronts.

A Biotech Story Worth Watching

With a first-in-class MS treatment advancing toward Phase 2 trials, a consumer product already on shelves and gaining market traction, and elite partnerships with global institutions like Harvard and AATAC — Quantum BioPharma stands apart in the small-cap biotech landscape.

It’s not just a company developing drugs. It’s building a platform for impact, backed by scientific validation and commercial momentum.


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