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NORTHBUD $NBUD.ca – Canadians spent $908M at #cannabis stores since legalization, StatCan says $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 5:30 PM on Wednesday, December 11th, 2019

SPONSOR: NORTHBUD (NBUD:CSE) Sustainable low cost, high quality cannabinoid production and procurement focusing on both bio-pharmaceutical development and Cannabinoid Infused Products. Learn More.

Canadians spent $908M at cannabis stores since legalization, StatCan says

  • Canadians spent $907,833 on non-medical cannabis between October 2018 and September 2019, the agency said, which works out to $24 per capita.

THE CANADIAN PRESS/Justin Tang

OTTAWA – Canadians spent about $908 million on non-medical cannabis in the first year since legalization, but online sales dropped as more brick-and-mortar locations opened, said Statistics Canada.

Canadians spent $907,833 on non-medical cannabis between October 2018 and September 2019, the agency said, which works out to $24 per capita.

Canada legalized cannabis on Oct. 17, 2018, becoming the second country in the world – after Uruguay – to legalize the drug. Demand initially appeared to outstrip supply as retailers warned of a pending shortfall of product.

Over the year, demand appeared to be highest in the sparsely populated Yukon where sales per capita led the other provinces and territories at $103, according to Statistics Canada. It was not able to provide data for Nunavut – the only area without a physical store.

Prince Edward Island sales per capita were the second highest at $97, while B.C. ranked lowest at $10.

Throughout the year, Canadians’ access to cannabis stores increased. The number of retail stores jumped from 217 this past March to 407 in July, according to the agency.

Alberta boasts the highest number of stores at 176 and B.C. took second place with 57 stores. Nunavut had the fewest with zero, followed by Prince Edward Island and the Yukon, both of which have four.

Nineteen per cent of Canadians lived three kilometres from a cannabis store as of July 2019. Thirty per cent lived 30 kilometres away and 45 per cent lived within 10 kilometres.

Albertans enjoyed the closest proximity to a store of any province, with half of the population living within three kilometres of a cannabis outlet. That figure rises to 63 per cent for five kilometres and 70 per cent for 10 kilometres.

Ontarians lived the furthest from cannabis stores on average. Nine per cent of the population resided three kilometres from a cannabis store. Eighteen per cent lived five kilometres away and 33 per cent were 10 kilometres away.

As the number of physical stores increased, the share of online sales dropped from 43.4 per cent in October 2018 to 5.9 per cent in September 2019.

“While online cannabis retail ensures access to all Canadians regardless of proximity to a physical store, accessibility continues to improve as more stores open across the country,” wrote Statistics Canada in its paper.

This report by The Canadian Press was first published Dec. 11, 2019.

Source: https://www.cp24.com/lifestyle/canadians-spent-908m-at-cannabis-stores-since-legalization-statcan-says-1.4725872

NORTHBUD $NBUD.ca – Brace for Impact: Industries on the Verge of #CBD Disruption $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 1:20 PM on Tuesday, December 10th, 2019

SPONSOR: NORTHBUD (NBUD:CSE) Sustainable low cost, high quality cannabinoid production and procurement focusing on both bio-pharmaceutical development and Cannabinoid Infused Products. Learn More.

North Bud Farms $NBUD.ca Announces Management Change and Corporate Update $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 7:55 PM on Monday, December 9th, 2019
  • On November 22nd, 2019, the Company received a request for information from Health Canada
  • The Request required the Company to provide certain information and confirmations related to the Company’s outstanding cultivation license application and evidence package
  • Company is pleased to report that the Request was responded to in full in advance of the December 8th, 2019 deadline.

TORONTO, Dec. 09, 2019 — North Bud Farms Inc. (CSE: NBUD) (OTCQB: NOBDF) (“NORTHBUD” or the “Company“) is pleased to announce the appointments of Mr. Ryan Brown as Executive Chairman of the Board of Directors, Mrs. Jennifer Ross-Carriere to the Board of Directors and Mr. Sean Homuth as Chief Executive Officer of the Company, effective immediately. 

“Since Sean has joined our team, he has been instrumental in structuring and closing the first round of our debenture financing as well as completing our acquisitions in California and Nevada,” said Ryan Brown, Executive Chairman of NORTHBUD. “As NORTHBUD evolves its operations in the USA, we are very excited in our future as 2020 will be a significant year of growth for the Company.  The extensive operational experience Sean brings to the team will be essential in executing our strategic plan and guiding the Company through its next level of growth. Moving forward NORTHBUD is committed to the highest level of financial management and diligence as we move from a pre-revenue startup into the revenue generating operational phase of development. Having someone with Sean’s experience and background at the helm of NORTHBUD’s day-to-day operations is a natural evolution for our Company. This transition will allow me to focus on overseeing the corporate strategy while supporting the management team in its execution.”

“We are also pleased to welcome Jennifer Ross-Carriere to our Board as she brings a strong legal and business background coupled with a wealth of corporate governance experience to our board,” said Ryan Brown. “Her knowledge, perspective and diverse skill set will complement our existing board members and be an incredible asset for our Company as we advance our strategic plan.”

Mr. Brown further stated, “I am pleased to take on the role of Executive Chairman supported by our first class independent Board of Directors consisting of Lead Independent Director and former Altria executive, Micheal Saxon, former multiple term Canadian Federal Cabinet Minister, Leona Aglukkat, Dr. Terresa DeLuca, Managing Director of the NY Life Science Venture Fund, Jennifer Ross-Carriere, and experienced capital markets executive and co-founder, André Audet.”   

“I am extremely pleased to be assuming the role of Chief Executive Officer working alongside Ryan, a seasoned veteran of our industry, as we move towards placing our vision into action,” said Sean Homuth, CEO of NORTHBUD. “Our strategy is to build a Company focused on operating cost-efficient cultivation facilities in the largest addressable markets in North America.  With a world class board and executive team, we are poised to lead NORTHBUD through a period of tremendous growth and opportunity.”

Annual and Special Meeting
The Company expects to hold its Annual and Special Meeting (the “Meeting”) in Ottawa, Ontario toward the last week of January 2020 or in early February 2020.  The Company will update shareholders and file the required notices on its website and under its issuer profile on SEDAR at www.sedar.com.

Corporate Update
On November 22nd, 2019, the Company received a request for information from Health Canada (the “Request”). The Request required the Company to provide certain information and confirmations related to the Company’s outstanding cultivation license application and evidence package. The Company is pleased to report that the Request was responded to in full in advance of the December 8th, 2019 deadline. The Request did not contain any notices of deficiencies in the Company’s cultivation license application nor did it require the Company to make any modifications to its facilities. On November 27th, senior management of the Company partook in a conference call with the Company’s assigned reviewer at Health Canada to ensure the completeness of the Company’s responses to the Request prior to submission. The Company is confident that the approval process is on track but, at this time, cannot predict when it will be granted a cultivation license by Health Canada. The Company will update shareholders on any material advancement of the application.

In preparation for the anticipated licensing of the Company’s Canadian production facility, the Company has entered into a purchase agreement with Ottawa-based licensed producer apollogreen inc.  apollogreen inc.’s business is focused on the sale of clones and starting genetics. Under the terms of the agreement, apollogreen inc. will provide the Company with starting materials which the Company expects to be cultivated and sold under its Business to Business (“B2B”) sales program.

“We are very happy to be working with the team at apollogreen whom we have known for many years,” said Ryan Brown. “Their services will significantly expedite our ability to achieve revenue post-receipt of our cultivation license. The Company is in negotiation with multiple licensed producers and expects to sign one or more letters of intent for wholesale B2B supply in the coming weeks. The Company’s intention is to secure immediate line of sight on revenue through the process of obtaining our direct sales licenses and preparing our unique genetics for commercialization under the NORTHBUD brand. Historically many producers have chosen to bank inventory for the first 12 months pending the receipt of a sales licence. We believe this is an inefficient strategy and has resulted in large inventory valuation write downs and inferior product being released to consumers. This provides us with a focused cultivation strategy from day one which will increase profitability and allow us to incrementally enter the market with higher-margin branded products while ensuring cash flow needs will be met in the near and medium term.” 

Option Grants
On December 9, 2019, the board of directors of the Company approved the grant of 1,025,000 incentive stock options (“Options”) to certain directors and senior officers of the Company. The Options vest immediately and are exercisable to acquire common shares of the Company at a price of $0.25 per common share, subject to the rules of the Canadian Securities Exchange (the “CSE”) and the Company’s newly adopted 2019 Omnibus Equity Incentive Compensation Plan (the “Omnibus Plan”). The Options expire five years from the date of grant. The Omnibus Plan was adopted by the Board of Directors on December 9, 2019 and is subject to ratification and approval by the shareholders of the Company at the Meeting. The foregoing grant of Options is subject to the ratification and approval of the Omnibus Plan.

RSU Grants
On December 9, 2019, the board of directors of the Company also approved the grant of 3,388,889 restricted share units (“RSUs”) to certain officers, directors, key employees and consultants of the Company. The RSUs vest in four equal tranches starting three months from the date of grant. Each vested RSU entitles the holder thereof to receive one common share of the Company upon delivery of an exercise notice, in accordance with the Omnibus Plan. The foregoing grant of RSUs is subject to the ratification and approval of the Omnibus Plan at the Meeting by the shareholders of the Company.

About Sean Homuth, CEO of NORTHBUD
Mr. Homuth brings extensive experience with both Canadian and U.S. publicly traded organizations both in industry as well as from a client perspective during his tenure at Ernst & Young and, more recently, as an independent consultant. Previously, Mr. Homuth was Chief Financial Officer at Orezone Gold Corporation (and Vice President, Finance and Administration for its predecessor company, Orezone Resources Inc.) a publicly listed company headquartered in Canada with operations in West Africa. At Orezone Mr. Homuth led a global team of finance professionals and was involved in over $800 million in financings and M&A transactions with the company and its predecessor. Mr. Homuth holds accounting designations in both Canada (CPA, CA) and the United States (CPA – Illinois).

About Jennifer Ross-Carriere, Director
Mrs. Ross-Carriere brings over 20 years of experience working with global companies in the technology industry providing strategic and operational advice to organizations of all sizes at the senior leadership and board levels with a particular emphasis on legal matters and employee relations. Previously, Mrs. Ross-Carriere held the roles as General Counsel and Vice-President, People & Culture at IFS Aerospace & Defense and General Counsel and Vice-President, People & Culture at Mxi Technologies. In these roles, she demonstrated strong skills in many areas including, intellectual property, licensing, M&A, corporate governance and employment. She is a senior HR professional with a focus on the development of an employee support organization truly matched to company culture.  Mrs. Ross-Carriere was called to the Bar of Ontario in 1999, holds a Bachelor of Laws (LL.B.) from McGill University and a Bachelor of Arts from Carleton University.  She has served as a Board member of several technology companies and non-profit organizations.

About North Bud Farms Inc.
North Bud Farms Inc., through its wholly owned subsidiary GrowPros MMP Inc., is pursuing a license under The Cannabis Act.  The Company has built a state-of-the-art purpose-built cannabis production facility located on 135 acres of Agricultural Land in Low, Quebec, Canada. NORTHBUD through its wholly owned U.S. subsidiary, Bonfire Brands USA has acquired cannabis production facilities in California and Nevada. The Salinas, California property is located on 11 acres which currently consists of a 300,000 sq. ft. of licensable greenhouse space with 60,000 sq. ft. actively cultivating cannabis and a 2,000 sq. ft. building licensed for distribution.  The Reno, Nevada property is located on 3.2 acres of land which was acquired through the acquisition of Nevada Botanical Science, Inc. a world class cannabis production, research and development facility with 5,000 sq. ft. of indoor cultivation which holds medical and adult use licenses for cultivation, extraction and distribution.

For more information visit: www.northbud.com

Neither the CSE nor its Regulation Services Provider (as that term is defined in the policies of the CSE) accepts responsibility for the adequacy or accuracy of this release.

Forward-looking statements
Certain statements and information included in this press release that, to the extent they are not historical fact, constitute forward-looking information or statements (collectively, “forward-looking statements”) within the meaning of applicable securities legislation.  Forward-looking statements, including those identified by the expressions “anticipate”, “believe”, “plan”, “estimate”, “expect”, “intend”, “may”, “should” and similar expressions to the extent they relate to the Company or its management.

Forward-looking statements, including those regarding the success of the Company’s license application, the Company’s ability to execute its strategic plan, conditions in the cannabis market, the Company’s shareholders approving the Omnibus Plan, the vesting of the RSUs, the Company entering agreements in connection with the B2B supply of cannabis and the Company’s transition into a revenue generating operational phase of development are based on the reasonable assumptions, estimates, analysis and opinions of management made in light of its experience and its perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances at the date that such statements are made, but which may prove to be incorrect.

Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, performance or achievements of the Company to differ materially from any future results, performance or achievements expressed or implied by the forward-looking statements.  Such risks and uncertainties include, among others, the risk factors included in the Company’s final long form prospectus dated August 21, 2018, which is available under the Company’s SEDAR profile at www.sedar.com. Accordingly, readers should not place undue reliance on any such forward-looking statements. Further, any forward-looking statement speaks only as of the date on which such statement is made. New factors emerge from time to time, and it is not possible for the Company’s management to predict all of such factors and to assess in advance the impact of each such factor on the Company’s business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. The Company does not undertake any obligation to update any forward-looking statements to reflect information, events, results, circumstances or otherwise after the date hereof or to reflect the occurrence of unanticipated events, except as required by law including securities laws. This news release does not constitute an offer to sell or a solicitation of any offer to buy any securities of the Company.

FOR ADDITIONAL INFORMATION, PLEASE CONTACT:
North Bud Farms Inc.
Edward Miller
VP, IR & Communications
Office: (855) 628-3420 ext. 3
[email protected] 

Empower Clinics $CBDT.ca – Researchers Leverage #CBD Medical Properties to Fight a Plethora of Ailments $WEED.ca $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 6:22 PM on Wednesday, December 4th, 2019

SPONSOR:

Why Empower Clinics

  • A leading owner/operator of physician staffed health and pain management clinics.
  • Patient database of over 165,000 patients 
  • Platform generating $1.4M USD (9 months ending Sept. 30, 2019)
  • Proprietary technology platforms including Electronic Health Records portal and e-Commerce for CBD product distribution
  • Recently launched CBD extraction facility
  • First extraction system capacity = 6,000 Kg per year.
  • CBD based products are poised to be a $20B global industry by 2022
  • Medical cannabis is poised to be a $100B global industry by 2025

——————

Researchers Leverage CBD’s Medical Properties to Fight a Plethora of Ailments

  • Over the past year, demand for cannabidiol, or CBD, has been increasing at an exponential pace.
  • In particular, the U.S. experienced massive growth in CBD sales after it passed the Farm Bill in late 2018, legalizing the commercialization of hemp, which CBD is derived from.
  • CBD is the active chemical found within the hemp plant, which falls under the cannabis family

NEW YORK, Dec. 4, 2019 — Over the past year, demand for cannabidiol, or CBD, has been increasing at an exponential pace. In particular, the U.S. experienced massive growth in CBD sales after it passed the Farm Bill in late 2018, legalizing the commercialization of hemp, which CBD is derived from. CBD is the active chemical found within the hemp plant, which falls under the cannabis family.

Similarly, marijuana also falls under the cannabis family, but marijuana and hemp are widely different in their biological makeup, as marijuana’s active chemical is THC, which is generally known to induce psychoactive effects. Meanwhile, CBD does not cause mind-altering effects but instead stimulates relaxation. Moreover, extensive clinical trials have also concluded that CBD can be effectively used in healthcare to treat a variety of medical conditions.

Consequently, many countries began to move towards legalizing CBD because of its versatile uses. For instance, researchers have boasted that CBD can treat symptoms associated with cancer, chronic pain, Alzheimer’s, multiple sclerosis, and epilepsy. However, in the U.S., there is currently only one CBD-based drug approved: Epidiolex. Epidiolex is used to treat Lennox-Gastaut and Dravet syndromes, which are two rare epileptic disorders that occur early in adolescence. And while the U.S. has only approved CBD for epilepsy-related conditions, other countries have legalized CBD-based drugs to treat other serious conditions such as HIV/AIDS, depression, and even withdrawal from opioid drugs.

Nevertheless, it is important to remember that the CBD industry is still in its infancy stage due to the lack of research authenticating the benefits of the compound. But researchers around the world are engaged in clinical trials to rectify this and prove the efficacy of CBD while promoting it as a next-generation medical treatment. According to data compiled by Grand View Research, the global cannabidiol market was valued at USD 1.34 Billion in 2018 and is expected to expand at a CAGR of 32.6% over the forecast period from 2019 to 2025.

Overall, there are hundreds of studies being conducted to evaluate the efficacy of CBD. Notably, researchers are advancing studies to further promote the use of the CBD for Parkinson’s treatment. Currently, the research on CBD for Parkinson’s is very limited and most studies are likely small-scale trials. However, the handful of studies that have been conducted suggest that CBD can have positive effects when dealing with nonmotor symptoms. According to Healthline, several studies have hinted that CBD can be used to treat tremors, psychosis, and improve the overall quality of life for some patients. For example, a small scale study suggested that CBD may help ease muscle movements, while another study discovered that CBD reduced the severity of individuals’ suffering from psychotic symptoms.

Meanwhile, another study suggested that CBD can help suppress sleep disturbances such as vivid dreams, nightmares, or movement. Additionally, several researchers even believe that CBD can ultimately be used to prevent Parkinson’s disease, even as there is currently insufficient data on the use of CBD on humans to prevent Parkinson’s. Nevertheless, researchers are actively evaluating the effects of CBD on protecting the human brain. And while research on CBD is limited, the small-scale results are highly promising.

As such, CBD clinical trials are anticipated to accelerate in the shortcoming future. “The work to date on marijuana and cannabinoids has given promising but conflicting signals,” said Rachel Dolhun, MD, Vice President, Medical Communications at The Michael J. Fox Foundation for Parkinson’s Research. “This therapy may represent a future treatment option for PD, but the correct dose and formulation are not clear, full side effects and drug interactions are unknown, and benefits have not been rigorously determined. Future studies should be large and well designed to provide clear data on the safety and efficacy of marijuana and cannabinoids in Parkinson’s.”

Source: https://www.ptcommunity.com/wire/researchers-leverage-cbds-medical-properties-fight-plethora-ailments

PRIMO Nutraceuticals Inc. $PRMO.ca – Demand For Hemp, #CBD Oil Could Result In A Christmas Tree Shortage $CROP.ca $VP.ca NF.ca $MCOA

Posted by AGORACOM-JC at 11:08 AM on Wednesday, December 4th, 2019

SPONSOR:  PRIMO NUTRACEUTICALS INC. (CSE: PRMO) (OTC: BUGVF) (FSE: 8BV) (DEU: 8BV) (MUN: 8BV) (STU: 8BV) provides strategic capital to the thriving cannabis cultivation sector through ownership and development of commercial real estate properties. The company also offers fully built out turnkey facilities equipped with state-of-the-art growing infrastructure to cannabis growers and processors. Click here for more info.

Demand For Hemp, CBD Oil Could Result In A Christmas Tree Shortage

  • The festive season has already begun! The US market is filled with Black Friday sales and it’s the merriest time of the year. 

By: Daniel Perry

But what’s interesting is the recent news that came from Texas about Christmas trees. Retailers are claiming Christmas trees might get sold out early in December as farmers are inclining towards cash-growing crops like hemp that is used to derive CBD oil- a potent and promising substance. 

Hemp has been trending in the US consumer market since December 2018 when the federal government legalized hemp. Companies have joined the CBD bandwagon offering numerous products ranging from CBD topicals, oils, creams, tincture, bath bombs, gummies, isolate, and what not! 

According to the retailers, the most healthy and big trees usually get sold out early in the festive season, right around Thanksgiving. With the shortage of Christmas trees this year, it is recommended for Texans to book their trees as soon as possible. 

With the inception of legal hemp farming, more and more farmers are exploring the CBD industry and investing their time in growing a cash crop with higher returns. Companies and big cooperation firms scout hemp for their CBD products from such farmers. Hemp is being considered as one of the most profitable crops of the year, as it is sold off at a much higher price as compared to other crops. 

The hemp industry has grown multifold over the past one year with CBD oil as one of its main products. Cannabidiol is a popular ingredient now available in skincare products with promises of increasing elasticity, promoting cell renewal and acting as an anti-aging compound. The cannabis-based beauty products are predicted to grab a piece of the $167 billion market.

Celebrities are touting CBD for its benefits, including Jennifer Aniston, Olivia Wilde, Busy Phillips, and the beauty mogul Kim Kardashian West. Even famous athletes such as Mike Tyson, David Wells, and KC Deane are endorsing CBD brands with products that promise faster recovery from accidents and a good healthy lifestyle overall. 

What Makes CBD So Popular?

CBD or cannabidiol is a hemp-derived substance that has anti-inflammatory, anti-oxidant and stress-relieving properties. Many people have touted CBD for its health benefits such as relieving stress, anxiety, depression, insomnia, back pain, acute ache, muscle injuries, ligament ruptures, arthritis, etc. It is also a potent drug in alleviating the symptoms of life-threatening ailments like cancer, epilepsy, Alzheimer’s and Tourettes. 

The US Food and Drug Administration has approved a cannabis-based medicine named Epidiolex, an oral solution that is used to treat two rare and severe forms of epilepsy- Dravet syndrome and Lennox Gastaut syndrome. These forms of epilepsy are most commonly found in children and experience numerous seizures that affect their overall growth. 

Cannabidiol is non-psychoactive in nature which means it does not produce any harmful mind-altering chemicals, like THC. THC or tetrahydro cannabidiol is the psychoactive component found in marijuana and its derivate plants that is responsible for the ‘high’ that people experience while smoking weed or hemp. It tends to produce a euphoric feeling which can dramatically affect mental health and might even cause permanent mental disorders. 

According to federal regulations, the maximum amount of THC per unit is 0.3%. This limit determines whether a cannabis-based product is safe for consumption or not. Any product containing higher than 0.3% per unit is marked as illegal and can be confiscated by enforcement officials. 

Recently, the FDA started sending out warning letters to companies that promote their cannabis-based products with medicinal promises or as an alternative to licensed medication. The FDA says that there’s a lot of research and background work that needs to be done in the field of cannabis, and promoting cannabis-based products without any relevant study or information is plainly misleading consumers. 

The agency warns customers to thoroughly read and be aware of the effects a cannabis-based product might have before they buy one. Also, it is recommended to buy only from licensed stores as their products are clinically tested, approved and safe for use.

Source: https://thecannabisradar.com/christmas-tree-shortage/7982/

Empower Clinics $CBDT.ca – Study: #CBD – Rich #Cannabis Can Treat ‘Multiple Symptoms’ of Autism $WEED.ca $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 4:45 PM on Friday, November 29th, 2019

SPONSOR:

Why Empower Clinics

  • A leading owner/operator of physician staffed health and pain management clinics
  • Patient database of over 165,000 patients 
  • Platform generating $4MM USD in revenue annually (2019)
  • Proprietary technology platforms including Electronic Health Records portal and e-Commerce for CBD product distribution
  • Launching CBD extraction facility
  • First extraction system capacity = 6,000 Kg per year.

Study: CBD-Rich Cannabis Can Treat ‘Multiple Symptoms’ of Autism

By Chris Roberts

It’s pure coincidence that autism—a broad term used to describe a spectrum of behaviors our society has deemed “aberrant”—became known and more widely diagnosed at the same time medical cannabis use was normalized in the United States.

The timing alone meant it was probably inevitable that weed would be used to try and “treat” autism, which affects one out of every 68 children born in the country and has no known “cure,” but there’s also the handy and salient fact that, according to a heap of anecdotal evidence, CBD-rich cannabis oil seems to help.

A growing body of clinical research attesting to cannabis’s success in treating autism continues to expand. In one of the latest studies, published in the most recent issue of the journal Frontiers in Neurology, patients with autism receiving “CBD-enriched” cannabis oil showed vast improvements in social interaction and communication, as well as other neurological benefits.

The first cannabis-based pharmaceutical drugs allowed in the United States have been to treat children with severe epilepsy. The conditions in the brain that lead to epileptic seizures may also somehow be related to the conditions—the “etiological mechanisms,” in researcher-speak—that lead to non-epileptic autism.

The cannabinoid that appears to treat these conditions is CBD, or cannabidiol, which appears to have value as a “neuroprotectant,” an intervention that allows the brain to function “better,” as well as an anti-inflammatory agent. So there’s some logic, as well as science, behind the approach.

In this most recent study, researchers in Brazil monitored the progress of 18 patients with autism over a period of up to nine months. Each of the patients received a CBD-rich cannabis sativa extract with a CBD to THC ratio of 75 to 1. The patients received 4.6 milligrams of CBD per kilogram of body weight to 0.06 milligrams of THC—a not insignificant dose for someone weighing more than 100 pounds.

Three patients discontinued the treatment because of “adverse effects” during the first month, but of the 15 who continued, 14 showed “some level of improvement” in multiple categories of symptoms.

Nine of the patients—the ones who did not also have epilepsy as well as autism—showed “improvement equal to or above 30%” in at least one of the categories monitored, and four patients showed significant improvement in at least four categories, including social interaction and function, as well as the ability to sleep and stay focused.

It’s hard to say with certainty whether the CBD was doing the work or was merely one tool in a box doing its share of the work. But as the researchers noted, 10 of the 15 patients were on other medications prior to starting the study—and nine of the 10 still showed improvement after cutting out or reducing their other, non-cannabis medications.

“The results reported here are very promising,” the researchers wrote, “and indicate that CBD-enriched [cannabis] may ameliorate multiple [autism spectrum disorder] symptoms even in non-epileptic patients, with substantial increase in life quality for both … patients and caretakers.”

As it happens, the pharmaceutical industry seems well aware of this potential: GW Pharmaceuticals, which patented and markets Epidiolex, the drug for epileptic children, is also working on developing a cannabis-derived drug that would be used to treat autism, as CNN’s Sanjay Gupta reported in September.

But this enthusiasm is not yet shared by researchers and doctors whose job it is to treat the condition.

“To date, there is limited research, and no evidence, on the potential short-term, long-term or neurodevelopmental risks and benefits of medical marijuana or its related compounds in ASD,” the Autism Science Foundation says on its website.

They’re not entirely wrong—there does need to be more evidence and successful clinical trials, including standardized dosing, before experts can endorse such a treatment—but it also seems clear that many parents and caretakers are unwilling to wait and happy to try cannabis. That’s why a growing number of states where medical cannabis is legal, including Texas, allow patients with autism to access cannabis oil.

Source: https://observer.com/2019/11/cbd-cannabis-autism-symptoms-study/

NORTHBUD $NBUD.ca – Consumers research #CBD more than many other wellness trends, study finds $CGC $ACB $APH $CRON.ca $HEXO.ca $OGI.ca

Posted by AGORACOM-JC at 10:12 AM on Thursday, November 28th, 2019

SPONSOR: NORTHBUD (NBUD:CSE) Sustainable low cost, high quality cannabinoid production and procurement focusing on both bio-pharmaceutical development and Cannabinoid Infused Products. Learn More.

Consumers research CBD more than many other wellness trends, study finds

  • American consumers are researching CBD more than many other alternative health trends and products, according to a new study looking at Google searches.

Health scientists from the University of California, San Diego, Johns Hopkins University in Baltimore and the University of York in the United Kingdom measured U.S. Google searches that mentioned CBD and cannabidiol from 2004 through April of this year.

The study found that while search volumes were consistent from 2004 to 2014, they began to grow significantly in 2016. Search volumes increased year-over-year by 125.9% in 2017 and 160.4% in 2018, and they are expected to be 117.7% higher in 2019.

In April 2019, there were 6.4 million Google searches for CBD, the researchers wrote in an American Medical Association journal detailing their findings.

The April 2019 searches for CBD were on par with yoga and e-cigarettes but seven times more prevalent than acupuncture, five times higher than apple cider vinegar and three times more than meditation.

CBD searches also outnumbered searches for:

  • Vaccination
  • Exercise
  • Marijuana
  • Veganism

Researchers broke down the results by state. Searches for CBD this year were highest in Vermont, Wisconsin, Tennessee, Colorado, New Hampshire and Oregon.

Source: https://hempindustrydaily.com/consumers-research-cbd-more-than-many-other-wellness-trends-study-finds/

PRIMO Nutraceuticals Inc. $PRMO.ca – #WHO Report Finds No Public Health Risks Or Abuse Potential For #CBD $CROP.ca $VP.ca NF.ca $MCOA

Posted by AGORACOM-JC at 10:38 AM on Wednesday, November 27th, 2019

SPONSOR:  PRIMO NUTRACEUTICALS INC. (CSE: PRMO) (OTC: BUGVF) (FSE: 8BV) (DEU: 8BV) (MUN: 8BV) (STU: 8BV) provides strategic capital to the thriving cannabis cultivation sector through ownership and development of commercial real estate properties. The company also offers fully built out turnkey facilities equipped with state-of-the-art growing infrastructure to cannabis growers and processors. Click here for more info.

WHO Report Finds No Public Health Risks Or Abuse Potential For CBD

  • According to a preliminary WHO report published last month, naturally occurring CBD is safe and well tolerated in humans (and animals), and is not associated with any negative public health effects [PDF].
  • Experts further stated that CBD, a non-psychoactive chemical found in cannabis, does not induce physical dependence and is “not associated with abuse potential.” The WHO also wrote that, unlike THC, people aren’t getting high off of CBD, either.  

By: Janet Burns

A World Health Organization (WHO) report has found no adverse health outcomes but rather several medical applications for cannabidiol, a.k.a. CBD, despite U.S. federal policy on this cannabinoid chemical.

According to a preliminary WHO report published last month, naturally occurring CBD is safe and well tolerated in humans (and animals), and is not associated with any negative public health effects [PDF].

Experts further stated that CBD, a non-psychoactive chemical found in cannabis, does not induce physical dependence and is “not associated with abuse potential.” The WHO also wrote that, unlike THC, people aren’t getting high off of CBD, either.  

“To date, there is no evidence of recreational use of CBD or any public health related problems associated with the use of pure CBD,” they wrote. In fact, evidence suggests that CBD mitigates the effects of THC (whether joyous or panicky), according to this and other reports.  

The authors pointed out that research has officially confirmed some positive effects of the chemical, however.

The WHO team determined that CBD has “been demonstrated as an effective treatment for epilepsy” in adults, children, and even animals, and that there’s “preliminary evidence” that CBD could be useful in treating  Alzheimer’s disease, cancer, psychosis, Parkinson’s disease, and other serious conditions.

The Herbal Chef CEO and Head Chef Chris Sayegh measures the dose of CBD cannabis extract as he… [+]

In acknowledgement of these kinds of discoveries in recent years, the report continued, “Several countries have modified their national controls to accommodate CBD as a medicinal product.” 

But the U.S., the report noted, isn’t one of them. As a cannabis component, CBD remains classified as a Schedule I controlled substance, meaning it has a “high potential for abuse” in the federal government’s view. Nevertheless, the “unsanctioned medical use” of CBD is fairly common, experts found.

For many CBD users in the U.S., the substance’s mostly unsanctioned and illegal state creates problems, especially as a wave of online (mostly hemp) and store-bought CBD oils and extracts have allowed patients to take the treatment process–and the risks involved in buying unregulated medicine–into their own hands and homes.

While CBD itself is safe and found to be helpful for many users, industry experts have warned that not all cannabis extracts are created equally, purely, or with the same methods of extraction.

And while reports of negative reactions to pure CBD are very few and far between, researchers are able to say that the cannabinoid wouldn’t be to blame alone. “Reported adverse effects may be as a result of drug-drug interactions between CBD and patients’ existing medications,” they noted.

As the cannabis reform nonprofit NORML reported, the WHO is currently considering changing CBD’s place in its own drug scheduling code. In September, NORML submitted written testimony to the U.S. Food and Drug Administration (FDA) opposing the enactment of international restrictions on access to CBD.

The FDA, which has repeatedly declined to update its position on cannabis products despite a large and ever-growing body of evidence on the subject, is one of a number of agencies that will be advising the WHO in its final review of CBD.

Perhaps this time around the FDA will listen, and learn something.

The report was presented by the WHO’s Expert Committee on Drug Dependence, and drafted under the responsibility of the WHO Secretariat, Department of Essential Medicines and Health Products, Teams of Innovation, Access and Use and Policy, Governance and Knowledge.

Source: https://www.forbes.com/sites/janetwburns/2018/03/18/who-report-finds-no-public-health-risks-abuse-potential-for-cbd/#7cde45562347

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Cannabis edibles preview: What to expect come mid-December

  • June 2019 report by Deloitte titled “Nurturing new growth: Canada gets ready for Cannabis 2.0” estimated the size of the edible and alternative cannabis product market could be “worth more than $2.5 billion a year and generate higher profits for retailers than cannabis products that are already legal.”

Edibles are on the way.

The 60-day Health Canada review period for cannabis edibles, extracts and topical products began counting down after the second wave of cannabis legalization across Canada came into effect Oct. 17.

With that review period set to end in mid-December, it won’t be long now before consumers can purchase and try all the new cannabis products licensed retailers are set to offer.

The Toronto Sun spoke with Sarah Gillin, COO of Etobicoke-based cannabis producer Olli Brands about what they have in store for customers.

“Olli is planning on launching with a strawberry real fruit chew, a butter cookie, a hemp crunch chocolate and five specialty tea blends — melo green, vanilla black, misty mint, sweet chamomile and my personal favourite, the berry bliss,” Gillin said, adding, “They will be offered in a variety of dosing options with CBD being featured prominently in almost all of them.”

This combo photo (top) shows Olli brands Butter Cookie edible and (bottom) their Misty Mint cannabis tea. Supplied

Gillin explained Olli partnered with Adrian Niman, a Michelin trained executive chef from The Food Dudes, to help develop and hand prepare the company’s edible products.

Olli will also be providing specialty cannabis teas. Gillin says Richard Guzauskas, Olli’s in-house “tea sommelier,” helps to internationally source the ingredients.

The “Sweet Chamomile Herbal Tea” is described on Olli’s website as a “Sweet and relaxing with an apple-honey aroma, this blend will lull you into calm.”

Canopy Growth Edibles and Beverages ‘Sneak Peek’ Tastings and Tours Beverages. Supplied photo jpg

Canopy Growth’s Tweed Inc. unveiled its line of 13 expected cannabis-infused beverages in late October. The low dosage “distilled cannabis” beverages are geared towards being consumed as a social beverage — with 10 designed to provide you with 2.5 mg of THC (Health Canada permits 10 mg per package).

Aurora Cannabis Inc., a Canadian owned licensed producer of medical and consumer cannabis gave eager edible consumers a sneak peek at a line of vapes they are working on last month as well.

They will come in three formats: a disposable vape pen, premium vape pen pods, and a pen with a universal cartridge system equipped with a rechargeable battery. They will be available for purchase on both the medical and consumer cannabis markets.

It’s worth noting, however, the U.S. Center for Disease Control identified vitamin E acetate as a “chemical of concern” among e-cigarette and vape users.

As of Nov. 20, 2019, the CDC stated there have been “2,290 cases of e-cigarette, or vaping product use” associated with lung injuries. The CDC recommends “people should not use THC-containing e-cigarette or vaping products, particularly from informal sources like friends, or family, or in-person or online dealers.”

Meanwhile, a June 2019 report by Deloitte titled “Nurturing new growth: Canada gets ready for Cannabis 2.0” estimated the size of the edible and alternative cannabis product market could be “worth more than $2.5 billion a year and generate higher profits for retailers than cannabis products that are already legal.”

“The edibles market alone is estimated to be worth at least $1.6 billion a year in Canada, with cannabis-infused beverages adding a further $529 million,” said Jennifer Lee, a partner and Deloitte Canada’s Cannabis National Leader.

Given the estimated size of the market, “It was not an easy choice,” Gillin said of choosing which edibles and alternative cannabis products to produce.

The review period has generally been frustrating for consumers.

Gillin said the 60 days has been “inconvenient” but also “necessary” to ensure ” the safety of consumers.”

Cannabis edibles will be available in mid-December. Chocolate Hemp Crunch, left, and Olli brands Strawberry Fruit Chews are two such products you will be able to get your hands on. Supplied

Source: https://torontosun.com/news/provincial/cannabis-edibles-preview-what-to-expect-come-mid-december

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Canadian Cannabis 2.0 is on its way and the U.S. is set to be the “biggest and the best cannabis market in the world”

By: Ruth Saldanha

Ruth Saldanha: Cannabis stocks in Canada have been a bit of a roller coaster recently. After a dramatic drop earlier this month, the stocks have somewhat recovered but are still trading below our fair value estimates. Is now a buying opportunity? Morningstar Analyst, Kristoffer Inton covers cannabis and is here today to talk about his views.

Kris, thank you so much for being here today.

Kristoffer Inton: Thank you for having me.

Saldanha: What’s going on with Canadian cannabis? Is the distribution the main culprit here?

Inton: Yeah, I think that’s one of the primary causes of what’s going on in Canadian distribution. I think also a part of it is investor expectations. So, I think people forget, this is a growth industry. These are all very early stage stocks. And when we look at where we are in terms of the growth cycle, we’ve only just past one year of recreational legalization. On top of that when you look at how Canada has been doing in terms of its rollout, you look at its two biggest provinces, Ontario and Quebec. They’ve really underperformed relative to expectations in terms of opening dispensaries. So, to us, it’s a little combination of slower than expected government rollout limiting demand growth and investor expectations for growth and even more so profitability a little too soon.

Saldanha: So, should Canadians consider investing in established U.S. retail players while we still wait for the market here to develop a bit more.

Inton: Yeah, I would definitely say so. I think that in our view, the U.S. is going to be the biggest and the best cannabis market in the world. And they operate in isolation the U.S. and Canada and so while the Canadian market continues to develop, you can also play and get investment exposure into the U.S. story as well. And because the U.S. distribution rollout has been a little bit smoother, it looks like growth and profitability are coming to American companies before it has come to for the Canadian companies.

Saldanha: After the recent drop in prices is now a buying opportunity for Canadian cannabis.

Inton: Definitely, I think that it definitely warrants a long-term view. In the near term, it’s not going to take overnight to open enough stores to get distribution right and to get the products lined up. So, it won’t happen in the next quarter or so. But if an investor is patient and willing to wait, they’ll be able to get exposure to a long runway of growth.

Saldanha: Finally, Kris, which is your top Canadian cannabis pick and why?

Inton: So, we recommend two Canadian picks. We like Aurora Cannabis (ACB) and we like Canopy Growth (WEED), really for two different reasons. Aurora Cannabis has largely been focused on production. And it shows their gross margins are the highest amongst the Canadian cannabis companies we cover. And we like Canopy Growth because we think that with the partnership with Constellation Brands, they’re really focused on developing downstream infused consumer products. With Cannabis 2.0 hitting Canada later this year and into next year, we think that Canopy is well exposed to being able to enjoy growth from that.

Saldanha: Thank you so much for being with us today, Kris.

Inton: Thank you.

Saldanha: For Morningstar, I’m Ruth Saldanha.

Source: https://www.morningstar.ca/ca/news/197539/time-to-buy-the-dip-on-cannabis.aspx